Effects of Progesterone, Testosterone, and Cortisol on Hypothalamic Prolactin-Inhibiting Factor and Pituitary Prolactin Content
- 1 February 1968
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 127 (2) , 426-429
- https://doi.org/10.3181/00379727-127-32707
Abstract
The effects of P, TP, and CA on hypothalamic PIF content, pituitary prolactin concentration, and mammary development were studied in mature ovariectomized rats. Each of the 3 steroids significantly decreased hypothalamic PIF content, increased pituitary prolactin concentration and, induced mammary growth. The TP and CA also elicited mammary secretion. These observations indicate that the stimulatory effect of the 3 hormones on pituitary prolactin secretion is mediated through the hypothalamus.This publication has 2 references indexed in Scilit:
- Prolactin Secretion in vitro: Effects of Gonadal and Adrenal Cortical Steroids.Experimental Biology and Medicine, 1964
- Depletion of Prolactin-Inhibiting Activity of Rat Hypothalamus by Estradiol or Suckling Stimulus11Endocrinology, 1964