Synthesis of 6-Substituted Purines From 3,7-Dimethyl-6-methylthio-2-oxopurine
- 1 January 1987
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1987 (03) , 278-280
- https://doi.org/10.1055/s-1987-27916
Abstract
Nucleophilic substitution of 3,7-dimethyl-6-methylthio-2-oxopurine (1) with alcoholates or carbanions of active methylene compounds affords the corresponding 6-alkoxy- or 6-alkylidene-3,7-dimethyl-2-oxopurines, respectively, in good yields.Keywords
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