The Effects of 14C Xylitol, Given Intravenously on the Serum-Glucose, Insulin and Lipid Concentrations of Male and Female Baboons

Abstract
When xylitol-U 14C is given intravenously to baboons, the incorporation of 14C into the serum glycerides is equal in the two sexes, and is of the same order as that found when fructose-U 14C is given intravenously to male baboons. Following xylitol injection, there is: (a) a marked rise in the serum insulin concentrations, these values being significantly greater in the male baboons than in the females; and (b) a fall in serum glucose concentration, which is of the same magnitude in both sexes. It is suggested that xylitol is converted to serum glyceride via the same metabolic pathways as glucose, and that the kinetics of this pathway are not sex-dependent.

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