Steroid Atrophy – A Histological Appraisal

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Abstract
The histological changes induced by 1 month’s applications of various corticosteroids to normal forearm skin were studied. Marked epidermal atrophy was present at 1 month with the more potent steroids, but the dermal changes were minimal or absent. The methods outlined in this study could serve as a useful model for assessing the unwanted atrophogenic action of potent corticosteroid preparations.

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