Synthesis and Anti-HIV Activity of 3'-Cyano-2',3'-dideoxythymidine and 3'-Cyano-2',3'-didehydro-2',3'-dideoxythymidine

Abstract
3''-Cyano-2'',3''-dideoxy- and 3''-cyano-2'',3''-didehydro-2'',3''-dideoxythymidines (4, 5) have been synthesized from 5-methyluridine (7). Anti-HIV activity of these compounds is also described.
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