The Bacteriophages of Pseudomonas pyocyanea: 1. The Effect of Various Substances upon their Development
- 1 May 1948
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 2 (2) , 154-161
- https://doi.org/10.1099/00221287-2-2-154
Abstract
Bacteriophages were isolated from several strains of P. pyocyanea and were assayed against an indicator strain. Counts of up to 1010 ml. were obtained in both broth and a defined medium. The phages are stable at 60[degree] but rapidly inactivated at 65[degree]. They are unaffected by 50% glycerol and are stable at pH 6.5-10 but not below 6.5. About 500 compounds have been tested for their inhibitory action on the development of these bacteriophages. All the sulfonamides, ami-dines, pyrimidines, organometallic compounds, plant extracts, mold cultures and antibiotics tested were inactive at concns. permitting growth of the host. Proflavine exerted a virustatic effect while notatin and H2O2 were lethal in a defined medium but not in broth.This publication has 3 references indexed in Scilit:
- Methods of Study of Antiphage Agents Produced by MicroorganismsJournal of Bacteriology, 1946
- BACTERIOPHAGIE ET VARIABILITE MICROBIENNE1946
- Notatin: an anti-bacterial glucose-aerodehydrogenase from Penicillium notatum Westling and Penicillium resticulosum sp. nov.Biochemical Journal, 1945