Resting pulmonary ventilation and dead space ventilation during the menstrual cycle.

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Abstract
By reanalyzing a previous study (Takano et al., 1981) of resting ventilation and PA[alveolar partial pressure]CO2 during the menstrual cycle of 8 healthy women, it was found that relative to the follicular phase a 9.4% increase in .ovrhdot.VA [alveolar ventilation] (P < 0.05) and a 2.5 mm Hg decrease in PACO2 (P < 0.001) occurring during the luteal phase, both of which were previously reported, were attributable mostly to a decrease in .ovrhdot.VD [dead space ventilation] (-7.2%, 0.05 < P < 0.1) but not to an increase in .ovrhdot.VE [expiratory ventilation] (+1.9%, N.S. [nonsignificant]). The latter 2 changes produced an 8.7% decrease in VD/VT [dead space-tidal volume ratio] (P < 0.01).

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