A Carbohydrate-Linked Cisplatin Analogue Having Antitumor Activity
- 14 June 1999
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 38 (12) , 1768-1769
- https://doi.org/10.1002/(sici)1521-3773(19990614)38:12<1768::aid-anie1768>3.0.co;2-6
Abstract
An unprotected and intact carbohydrate moiety has been observed for the first time in a transition metal complex. The carbohydrate-linked platinum(II) complex cis-dichloro[(2-β-D-glucopyranosidyl)propane-1,3-diamine]platinum (see picture) is an analogue of cisplatin and exhibits comparable antitumor activity along with increased solubility in water.This publication has 0 references indexed in Scilit: