CYTOGENETICS OF HUMAN-SPERM - MEIOTIC SEGREGATION IN 2 TRANSLOCATION CARRIERS
- 1 February 1986
- journal article
- research article
- Vol. 38 (2) , 197-208
Abstract
Meiotic segregation products were studied in sperm from two men heterozygous for the reciprocal translocations t(8;15)(p22;q21) and t(3;16)(p23;q24). A total of 226 and 201 sperm complements, respectively, were analyzed. In each translocation, 63% of complements were unbalanced, and alternate and adjacent 1 percentages were similar. The 3:1 segregation frequencies produced by the two translocations were 3.5% and 5.0%.This publication has 19 references indexed in Scilit:
- Chromosome segregation into the spermatozoa of two men heterozygous for different reciprocal translocationsHuman Genetics, 1983
- Chromosome abnormality in couples with histories of multiple abortions. The outcome of pregnancies subsequent to ascertainment and a study of familial translocation carriersHuman Genetics, 1983
- Reciprocal translocation with special reference to reproductive failureHuman Genetics, 1980
- Reciprocal translocations: A way to predict the mode of imbalanced segregation by pachytene-diagram drawingHuman Genetics, 1980
- Anatomic and chromosomal anomalies in 639 spontaneous abortusesHuman Genetics, 1980
- Direct analysis of the chromosome constitution of human spermatozoaNature, 1978
- Cytogenetics of aborters and abortusesAmerican Journal of Obstetrics and Gynecology, 1978
- Familial balanced translocation 4p+/17q- as a suggested cause of primary trisomy-21 Down's syndrome.Archives of Disease in Childhood, 1977
- Reciprocal translocations in man. 3:1 Meiotic disjunction resulting in 47- or 45-chromosome offspring.Journal of Medical Genetics, 1975
- RECIPROCAL TRANSLOCATIONSBritish Medical Bulletin, 1969