Navigating the signalling network in mouse cardiac myocytes
- 1 December 2002
- journal article
- overview
- Published by Springer Nature in Nature
- Vol. 420 (6916) , 712-714
- https://doi.org/10.1038/nature01306
Abstract
Cardiac myocytes have a complex network of signals that regulates their essential role in the rhythmic pumping of the heart. This network is an appealing model system in which to study the basic principles underlying cellular signalling mechanisms. Progress in this effort has come through the establishment of standardized myocyte isolation and culture procedures and characterization of important signalling responses.Keywords
This publication has 25 references indexed in Scilit:
- Dual Site Phospholamban Phosphorylation and Its Physiological Relevance in the HeartTrends in Cardiovascular Medicine, 2002
- Seven-transmembrane-spanning receptors and heart functionNature, 2002
- Mechanism for Nucleocytoplasmic Shuttling of Histone Deacetylase 7Journal of Biological Chemistry, 2001
- Compartmentation of G Protein-Coupled Signaling Pathways in Cardiac MyocytesAnnual Review of Pharmacology and Toxicology, 2001
- G-proteins in growth and apoptosis: lessons from the heartOncogene, 2001
- Characterization of G-protein Signaling in Ventricular Myocytes From the Adult Mouse Heart: Differences From the RatJournal of Molecular and Cellular Cardiology, 2000
- Functional Consequences of Altering Myocardial Adrenergic Receptor SignalingAnnual Review of Physiology, 2000
- Signaling Pathways for Cardiac Hypertrophy and FailureNew England Journal of Medicine, 1999
- Multiple Effects of 2,3‐Butanedione MonoximeBasic & Clinical Pharmacology & Toxicology, 1994
- Cardiomyocytes of adult mice in long-term cultureThe Science of Nature, 1993