Demonstration of γ-trace in normal endocrine cells of the adrenal medulla and in phaeochromocytoma

Abstract
.gamma.-Trace was demonstrated by the immunohistochemical peroxidase/antiperoxidase technique to occur in normal chromaffin cells of the adrenal medulla from African green monkey, capuchin monkey and beagle dog and in the cells of a norepinephrine-producing human pheochromocytoma. The presence of .gamma.-trace in the endocrine epithelial cells of the adrenal medulla suggests that .gamma.-trace might be related to the neuroendocrine system.