Novel Cytotoxic Principles of Formosan Ganoderma lucidum
- 1 July 1991
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 54 (4) , 998-1002
- https://doi.org/10.1021/np50076a012
Abstract
Two new steryl esters, ergosta-7,22-dien-3 beta-yl linoleate [1] and 5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-yl linoleate [3], and a novel steroid, ergosta-7,22-diene- 3 beta,3 alpha,9 alpha-triol [5], have been isolated from the fruiting bodies of Formosan Ganoderma lucidum and characterized. A new lanostanoid, 3 beta-hydroxy-26-oxo-5 alpha-lanosta- 8,24-dien-11-one, and the new steroid exhibited potent inhibition of KB cells and human PLC/PRF/5 cells in vitro.Keywords
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