Apoptosis--the Calcium Connection
Top Cited Papers
- 4 April 2003
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 300 (5616) , 65-67
- https://doi.org/10.1126/science.1083628
Abstract
Calcium ions are crucial to many cellular processes including apoptosis. In their Perspective, [Demaurex and Distelhorst][1] explain new work that shows how calcium ions flowing between the endoplasmic reticulum (ER) and mitochondria regulate programmed cell death, highlighting the ER as a new gateway to apoptosis ([ Scorrano et al .][2]). [1]: http://www.sciencemag.org/cgi/content/full/300/5616/65 [2]: http://www.sciencemag.org/cgi/content/short/300/5616/135Keywords
This publication has 23 references indexed in Scilit:
- BAX and BAK Regulation of Endoplasmic Reticulum Ca 2+ : A Control Point for ApoptosisScience, 2003
- Mitochondria Recycle Ca2+ to the Endoplasmic Reticulum and Prevent the Depletion of Neighboring Endoplasmic Reticulum RegionsJournal of Biological Chemistry, 2001
- Breaking the mitochondrial barrierNature Reviews Molecular Cell Biology, 2001
- Control of apoptosis by IP3and ryanodine receptor driven calcium signalsCell Calcium, 2000
- The versatility and universality of calcium signallingNature Reviews Molecular Cell Biology, 2000
- Apoptosis driven by IP3-linked mitochondrial calcium signalsThe EMBO Journal, 1999
- Mitochondria and ApoptosisScience, 1998
- Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytesNature, 1995
- Decoding of cytosolic calcium oscillations in the mitochondriaCell, 1995
- Microdomains with High Ca 2+ Close to IP 3 -Sensitive Channels that Are Sensed by Neighboring MitochondriaScience, 1993