Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan
- 14 October 2003
- Vol. 22 (8) , 909-914
- https://doi.org/10.1016/j.vaccine.2003.09.012
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Protective Levels of Diphtheria-Neutralizing Antibody Induced in Healthy Volunteers by Unilateral Priming-Boosting Intranasal Immunization Associated with Restricted Ipsilateral Mucosal Secretory Immunoglobulin AInfection and Immunity, 2003
- Immunization withHaemophilus influenzaeType b–CRM197Conjugate Vaccine Elicits a Mixed Th1 and Th2 CD4+T Cell Cytokine Response That Correlates with the Isotype of Antipolysaccharide AntibodyThe Journal of Infectious Diseases, 2001
- A mucosal vaccine against diphtheria: formulation of cross reacting material (CRM197) of diphtheria toxin with chitosan enhances local and systemic antibody and Th2 responses following nasal deliveryVaccine, 2000
- The sero-epidemiology of diphtheria in Western EuropeEpidemiology and Infection, 2000
- Implications of the Diphtheria Epidemic in the Former Soviet Union for Immunization ProgramsThe Journal of Infectious Diseases, 2000
- Mucosal immunity and tolerance: relevance to vaccine developmentImmunological Reviews, 1999
- The expanding universe of T-cell subsets: Th1, Th2 and morePublished by Elsevier ,1999
- Distinct T‐cell subtypes induced with whole cell and acellular pertussis vaccines in childrenImmunology, 1998
- Intranasal booster vaccination against diphtheria and tetanus in manVaccine, 1997
- Chitin Biotechnology ApplicationsBiotechnology Annual Review, 1996