Cystic Fibrosis Gene Therapy Trials and Tribulations

This publication has 12 references indexed in Scilit:

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  Molecular Therapy, 2000
• The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium
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• EnhancedIn VivoAirway Gene Transfer via Transient Modification of Host Barrier Properties with a Surface-Active Agent
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• A Pilot Clinical Trial of Oral Sodium 4-Phenylbutyrate (Buphenyl) in Δ F508-Homozygous Cystic Fibrosis Patients
  American Journal of Respiratory and Critical Care Medicine, 1998
• Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.
  Journal of Clinical Investigation, 1997
• Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
  Gene Therapy, 1997
• Loss of Binding and Entry of Liposome-DNA Complexes Decreases Transfection Efficiency in Differentiated Airway Epithelial Cells
  Journal of Biological Chemistry, 1997
• In Vivo Nasal Potential Difference: Techniques and Protocols for Assessing Efficacy of Gene Transfer in Cystic Fibrosis
  Human Gene Therapy, 1995
• Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
  Nature Medicine, 1995
• Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
  Nature Genetics, 1992