Graded changes in central chemoreceptor input by local temperature changes on the ventral surface of medulla
- 31 January 1979
- journal article
- research article
- Published by Wiley in The Journal of Physiology
- Vol. 287 (1) , 191-211
- https://doi.org/10.1113/jphysiol.1979.sp012654
Abstract
In cats under pentobarbitone anesthesia the effects of focal temperature changes of the chemoceptive areas on the ventral surface of medulla were studied with respect to tidal volume (VT), tidal variation in efferent phrenic activity, (PhrT) and respiratory rate. The close similarities in effect of focal cooling and of hypocapnia on the different respiratory parameters even during constant artificial ventilation indicate that focal temperature changes of the intermediate (I(S)) areas intervene effectively with the normal ventilatory response to CO2 without changing the chemical or physical environment of those neural structures in the brain stem which set respiratory pattern.This publication has 38 references indexed in Scilit:
- Excitability Changes of the Inspiratory ‘Off‐switch’ Mechanism Tested by Electrical Stimulation in Nucleus Parabrachialis in the CatActa Physiologica Scandinavica, 1976
- Effects of Lesions in the Parabrachial Nucleus on the Mechanisms for Central and Reflex Termination of Inspiration in the CatActa Physiologica Scandinavica, 1976
- Steady State Effects of CO2 and Temperature on the Relationship between Lung Volume and Inspiratory Duration (Hering‐Breuer Threshold Curve)Acta Physiologica Scandinavica, 1974
- Transient and Steady State Effects of C02 on Mechanisms Determining Rate and Depth of BreathingActa Physiologica Scandinavica, 1974
- Respiratory neurones of the ventrolateral nucleus of the solitary tract of cat: Vagal input, spinal connections and morphological identificationBrain Research, 1973
- Histological structures in the chemosensitive regions on the ventral surface of the cat's medulla oblongataPflügers Archiv - European Journal of Physiology, 1973
- Effects of local cooling upon conduction and synaptic transmissionBrain Research, 1972
- Effects on respiration and circulation of electrically stimulating the ventral surface of the medulla oblongataRespiration Physiology, 1970
- The effect of local cooling upon spontaneous and evoked electrical activity of cerebral cortexCanadian Journal of Physiology and Pharmacology, 1970
- Efferent control of the carotid body chemoreceptorCellular and Molecular Life Sciences, 1970