A RABIES VACCINE FROM HAMSTER KIDNEY TISSUE CULTURES: PREPARATION AND EVALUATION IN ANIMALS
- 1 December 1960
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 6 (6) , 605-609
- https://doi.org/10.1139/m60-072
Abstract
A strain of fixed rabies virus adapted to hamster kidney tissue cells has produced culture fluids of high infectivity for rabbits and mice. These culture fluids were rendered non-infective by treatment with formaldehyde at a concentration of 8 m M. Rabbits immunized with this material produced autirabies antibody to a high titer and were subsequently proved to be resistant to intramuscular inoculation of rabies virus from the salivary glands of a naturally infected fox.Keywords
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