This is the 1st patient report of maternal ingestion of anticonvulsants associated with the triad of fetal hydantoin syndrome, neuroblastoma and hemorrhagic disease. The neuroblastoma, a neural crest tumor, is the 4th of such origin reported after in utero exposure to phenytoin. This suggests that phenytoin is a transplacental carcinogen. Infants of epileptic mothers receiving anticonvulsants should be closely examined at birth for the fetal hydantoin syndrome and monitored for hemorrhagic problems. The neural crest tumor may be found at birth or later in childhood.