Stop-flow studies on renal handling of lithium ions in the dog
- 1 November 1962
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 203 (5) , 897-900
- https://doi.org/10.1152/ajplegacy.1962.203.5.897
Abstract
Stop-flow experiments were performed on dogs after serum Li concentrations had been raised to 10–21 mEq/liter with intravenous infusions of Li salts. Li is actively reabsorbed at a distal portion of the nephron close to the site of sodium and potassium reabsorption. Li may cause alkalinization of the urine by inhibiting H+ secretion. Stimulation of K secretion by Li could not be demonstrated. Li may reduce K reabsorption.Keywords
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