Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1
Open Access
- 1 March 2005
- journal article
- research article
- Published by Elsevier in Journal of Lipid Research
- Vol. 46 (3) , 526-534
- https://doi.org/10.1194/jlr.m400400-jlr200
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Niemann-Pick C1 Like 1 (NPC1L1) Is the Intestinal Phytosterol and Cholesterol Transporter and a Key Modulator of Whole-body Cholesterol HomeostasisJournal of Biological Chemistry, 2004
- Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol AbsorptionScience, 2004
- Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activityBioorganic & Medicinal Chemistry Letters, 2003
- Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in miceBiochemical Journal, 2003
- Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrationsJournal of Lipid Research, 2003
- Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyteJournal of Lipid Research, 2002
- Increased Hepatobiliary and Fecal Cholesterol Excretion upon Activation of the Liver X Receptor Is Independent of ABCA1Journal of Biological Chemistry, 2002
- Fatty Acid Homeostasis and Induction of Lipid Regulatory Genes in Skeletal Muscles of Peroxisome Proliferator-activated Receptor (PPAR) α Knock-out MiceJournal of Biological Chemistry, 2002
- Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient miceGastroenterology, 1998
- Preferential Utilization of Free Cholesterol From High-Density Lipoproteins for Biliary Cholesterol Secretion in ManScience, 1978