Less Platelet Damage in the Curved Vane Centrifugal Pump: A Comparative Study with the Roller Pump in Open Heart Surgery

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Abstract
The centrifugal pump with the curved vane (Lifestream Centrifugal Pump [LCP]) was applied to cardiopulmonary bypass (CPB) in 10 patients who underwent elective coronary artery bypass grafting. Serum hemoglobin levels, platelet counts, and serum β–thromboglogulin (β–TG) levels were measured during CPB. The results were compared with those for a comparative roller pump (RP) group (n = 10). There was no difference in CPB time between LCP (112 ± 22 min) and RP (121 ± 22 min) groups. Serum β–TG levels (ng/ml) were lower in the LCP group than in the RP group (34 ± 9 vs. 101 ± 80, 5 min; 81 ± 33 vs. 236 ± 112, 30 min; 120 ± 53 vs. 314 ± 100, 60 min after initiation of CPB; p < 0. 05). There were no significant differences in hemolysis and platelet depletion. The LCP showed excellent hemodynamic performance with less blood trauma in clinical application to open heart surgery.