Curved DNA without AA/TT dinucleotide step
Open Access
- 1 January 1991
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 19 (13) , 3549-3551
- https://doi.org/10.1093/nar/19.13.3549
Abstract
The evidence is accumulating that dinucleotide steps other than AA/TT affect DNA flexure of AnTm (m+n>=4) containing fragments. However, It is not clear whether macroscopic DNA flexure without AA/TT steps might occur. In this paper we demonstrate the anomaly in electrophoretic mobility of non AA/TT repetitive DNA sequences which is a function of sequence phasing. Therefore, our results show that PyPu (TA) and AG/CT steps, angulary separated by close to 180 degrees from Pu/Py (GC) and GG/CC steps, bend DNA, even in the absence of AnTm tracts.Keywords
This publication has 27 references indexed in Scilit:
- New insights into the structure of An tracts and B'-B' bends in DNABiochemistry, 1991
- Sequence-Dependent Kinks Induced in Curved DNAJournal of Biomolecular Structure and Dynamics, 1990
- Structure of an alternating-B DNA helix and its relationship to A-tract DNA.Proceedings of the National Academy of Sciences, 1988
- DNA curvature in native and modified EcoRI recognition sites and possible influence upon the endonuclease cleavage reactionJournal of Molecular Biology, 1988
- The intrinsic curvature of DNA in solutionJournal of Molecular Biology, 1988
- Calibration of DNA curvature and a unified description of sequence-directed bending.Proceedings of the National Academy of Sciences, 1988
- Structural details of an adenine tract that does not cause DNA to bendNature, 1988
- DNA bending at adenine · thymine tractsNature, 1986
- Curved DNA: design, synthesis, and circularization.Proceedings of the National Academy of Sciences, 1986
- Bent helical structure in kinetoplast DNAProceedings of the National Academy of Sciences, 1982