Anticipating epileptic seizures in real time by a non-linear analysis of similarity between EEG recordings
- 1 July 1999
- journal article
- clinical trial
- Published by Wolters Kluwer Health in NeuroReport
- Vol. 10 (10) , 2149-2155
- https://doi.org/10.1097/00001756-199907130-00028
Abstract
IN a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term nonstationarity in the EEG by a measure of dynamical similarity between different parts of the time series. We apply this method to the study of a group of patients with temporal lobe epilepsy recorded intracranially during transitions to seizure. We show that the method, which can be implemented on a personal computer, can track in real time spatio-temporal changes in brain dynamics several minutes prior to seizure.Keywords
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