INTRAFAMILIAL CORRELATION ANALYSIS FOR IGM SERUM LEVELS
- 1 January 1977
- journal article
- research article
- Vol. 29 (6) , 571-574
Abstract
The Ig[immunoglobulin]M serum level was determined in the members of 29 healthy families. The IgM mean concentrations between fathers and mothers and between sons and daughters were significantly different (P < .01), with higher serum IgM levels in females than in males. Simple linear regression analysis was done for the following intrafamilial combinations: son-father, daughter-father, son-mother, and daughter-mother. Significant correlation coefficients (P < .05) were obtained in all 4 combinations, which does not support the X-linked gene hypothesis (i.e., that the X chromosome carries quantitative genes for IgM). An alternative explanation for the differences between sexes for IgM serum concentration is considered.This publication has 16 references indexed in Scilit:
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