OKADAIC ACID - A VALUABLE NEW TOOL FOR THE STUDY OF SIGNAL TRANSDUCTION AND CELL-CYCLE REGULATION
- 1 January 1992
- journal article
- review article
- Vol. 4 (1) , 16-21
Abstract
Okadaic acid is beginning to find its way into laboratories that study cellular control of gene expression and proliferation. By virtue of its specific inhibitory effects on certain protein phosphatases it seems to be a powerful tool for the analysis of regulatory phosphorylation-dephosphorylation events. Here, some of the important new findings with the use of this drug are summarized, and a few potential drawbacks of its application discussed.Keywords
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