OSTEITIS TUBERCULOSA MULTIPLEX CYSTICA OF FIBULA AND TIBIA
- 14 April 1934
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 102 (15) , 1206-1208
- https://doi.org/10.1001/jama.1934.02750150010003
Abstract
Following its introduction by Jüngling1in 1920, the term "osteitis tuberculosa multiplex cystica" was applied to cystlike degeneration of the bones without joint involvement, characterized by the gradual onset of mild pain and swelling of the affected parts, distinctive roentgenographic observations and a chronic benign course. Not infrequently associated were lupus pernio and Boeck's sarcoid. Histologically, the bone showed epithelioid and giant cell tubercles, with little or no caseation. Tubercle bacilli were rarely demonstrated in examined tissue; guinea-pig inoculation occasionally gave positive results for tuberculosis. In the past year Van Alstyne and Gowen,2reviewing the literature on osteitis tuberculosa multiplex cystica, stated that in all the reported cases the condition was restricted to the small bones of the hands or feet. Theirs was the first authentic case presenting typical lesions in the long bones. They presented a white man, aged 32, who exhibited destructive changes in the leftKeywords
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