Myocardial infarction due to postirradiation fibrosis of the coronary arteries. Case of successfully treated Hodgkin's disease with lower esophageal involvement

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Abstract
A patient with Hodgkin''s disease of 18 years duration died ultimately of pulmonary impairment secondary to pulmonary Hodgkin''s disease, fibrosis, and bronchopneumonia. He received radiation therapy to the lower esophagus and mediastinum, and 2 months later had an acute myocardial infarction. This was caused by fibrous occlusion of the right coronary artery, similar to the process observed clinically and experimentally in medium and small arteries exposed to radiation. This is probably the first case of acute myocardial infarction due to subintimal fibrous proliferation of the coronary arteries to be studied pathologically.

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