Antibiotics from basidiomycetes. X. Scorodonin, a new antibacterial and antifungal metabolite from Marasmius scorodonius (Fr.) Fr.
- 1 January 1980
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 33 (5) , 463-467
- https://doi.org/10.7164/antibiotics.33.463
Abstract
Scorodonin, a novel biologically active metabolite, was isolated from submerged cultures of the mushroom M. scorodonius (Fr.) Fr. Its structure was determined by chemical and physical methods. The antibiotic inhibits the growth of bacteria, yeasts and filamentous fungi. In cells of the ascitic form of Ehrlich carcinoma, the incorporation of thymidine and uridine into DNA and RNA is strongly inhibited by scorodonin, whereas the incorporation of leucine into protein is not affected.This publication has 5 references indexed in Scilit:
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