Halogen Selectivity in Nickel Salt-Catalyzed Cross-Coupling of Aryl Grignard Reagents with Bromochlorobenzenes a Novel Synthetic Method of Unsymmetrical Terphenyl
- 1 February 1991
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 21 (3) , 481-487
- https://doi.org/10.1080/00397919108016772
Abstract
The reactions of aryl Grignard reagents with p- and m-bromochlorobenzenes catalyzed by non-ligated NiCl2 give selectively chlorobiphenyl derivatives. By the stepwise reaction, an unsymmetrical terphenyl was synthesized in a good yield.Keywords
This publication has 6 references indexed in Scilit:
- Non-ligated Nickel Chloride-Catalyzed Cross-Coupling of Aromatic Grignard Reagents with Aryl HalidesSynthesis, 1990
- A palladium-catalyzed stereospecific substitution reaction of homoallylzincs with .beta.-bromo-substituted .alpha.,.beta.-unsaturated carbonyl derivatives. A highly selective synthesis of mokupalideThe Journal of Organic Chemistry, 1980
- Nickel and palladium complex catalyzed cross-coupling reactions of organometallic reagents with organic halidesPure and Applied Chemistry, 1980
- Synthesis of unsymmetrical biphenyls via aryl-substituted 1,4-cyclohexadienesThe Journal of Organic Chemistry, 1978
- Selective carbon-carbon bond formation by cross-coupling of Grignard reagents with organic halides. Catalysis by nickel-phosphine complexesJournal of the American Chemical Society, 1972
- Activation of Grignard reagents by transition-metal complexes. A new and simple synthesis of trans-stilbenes and polyphenylsJournal of the Chemical Society, Chemical Communications, 1972