MECHANISM OF RENAL ELIMINATION OF 2 ELEMENTS OF GROUP IIIA OF THE PERIODIC TABLE

  • 1 January 1981
    • journal article
    • research article
    • Vol. 292  (1) , 91-+
Abstract
Al and In, 2 elements of group III A of the periodic table, are concentrated by the kidney inside lysosomes of proximal tubule cell. In these lysosomes, Al and In are precipitated as non-soluble phosphate salts and these precipitates are then expelled in the tubular lumen and eliminated with the urinary flow. These data were visualized by analytical microscopy (ion microscopy and X-ray microanalysis). Local acid phosphatases are assumed to permit the concentration of Al and In salts inside the lysosomes.

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