Immunogenic properties of Staphylococcus aureus and Streptococcus agalactiae administered separately and in combination to lactating cows

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Abstract
Composite bacterins of Staphylococcus aureus and Streptococcus agalactiae, or either bacterin alone, were administered systemically to groups of lactating cows. The response to each bacterin was unaffected by the simultaneous administration of the antigens when assessed by comparing the antibody levels in milk by enzyme-linked immunosorbent assay. There was no evidence of cross reactivity of the antigens studied, nor immunopotentiation by either bacteria.