Control of Endemic Methicillin-Resistant Staphylococcus aureus

Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) has become endemic worldwide over the past 2 decades,1-3 and is now a major nosocomial pathogen in many hospitals.3,4 There are wide variations among countries and hospitals. In Europe, recent surveys indicate that the proportion of MRSA varies from 30% to 40% in southern countries to less than 1% in some northern countries,2 in which sustained MRSA control programs have been implemented early.5,6 High-risk units, such as intensive care units (ICUs), are most affected. In 1992, MRSA accounted for 57% of all ICU-acquired S aureus infections recorded in the European Prevalence of Infection in Intensive Care study.7

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