FAP1, a homologue of human transcription factor NF‐X1, competes with rapamycin for binding to FKBP12 in yeast
Open Access
- 1 September 2000
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 37 (6) , 1480-1493
- https://doi.org/10.1046/j.1365-2958.2000.02105.x
Abstract
The immunosuppressive drug rapamycin binds to the peptidyl‐prolyl cis‐trans isomerase FKBP12, and this complex arrests growth of yeast cells and activated T lymphocytes in the G1 phase of the cell cy...Keywords
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