Detection of α-Transducin in Retinal Rods But Not Cones
- 21 February 1986
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 231 (4740) , 856-859
- https://doi.org/10.1126/science.3080807
Abstract
The distribution in chicken retina of the α subunit of transducin, the guanine nucleotide-binding protein that couples light-dependent activation of rhodopsin with activation of guanosine 3′,5′-monophosphate phosphodiesterase, was determined with the aid of a specific antiserum. α-Transducin was found in rod photoreceptor cells but was not detected in cones. These results show that rods and cones differ with respect to α-transducin content and suggest that the processes of phototransduction may differ correspondingly in rods and cones.This publication has 25 references indexed in Scilit:
- Cyclic GMP increases photocurrent and light sensitivity of retinal conesNature, 1985
- Cyclic GMP-sensitive conductance in outer segment membrane of catfish conesNature, 1985
- Vision: Phototransduction changes focusNature, 1985
- Primary structure of the α-subunit of transducin and its relationship to ras proteinsNature, 1985
- Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation FactorsScience, 1985
- Phototransduction in Vertebrate RodsAnnual Review of Neuroscience, 1985
- Sensory and energy transduction: Light-activated retinal proteinsNature, 1984
- Detection of a light-sensitive pool of cGMP in goldfish cone color receptors by immunocytochemistry.Journal of Histochemistry & Cytochemistry, 1983
- Scanning electron microscopy of developing photoreceptors in the chick retinaThe Anatomical Record, 1979
- Symmetry in a receptor mosaic demonstrated in the chick from the frequencies, spacing and arrangement of the types of retinal receptorJournal of Comparative Neurology, 1970