Abstract
The life cycle of Theromyzon tessulatum has been divided into stages defined on the basis of feeding pattern and reproductive activity. The use of an antiserum raised against porcine motilin demonstrated the presence of immunoreactive cells and fibers in the supraesophageal ganglion throughout the life of the leech. Immunopositive fibers are present in the neurohemal area of the dorsal commissure. The highest number of immunopositive neurons is found during stages 3B, 3C and 3D, which precede egg-laying. The control of oogenesis by a substance related to porcine motilin is postulated.

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