Identification of the Vibrio vulnificus wbpP Gene and Evaluation of Its Role in Virulence
Open Access
- 1 January 2006
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 74 (1) , 721-728
- https://doi.org/10.1128/iai.74.1.721-728.2006
Abstract
A wbpP gene encoding a putative UDP- N -acetyl- d -glucosamine C 4 epimerase was identified and cloned from Vibrio vulnificus . The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus .Keywords
This publication has 30 references indexed in Scilit:
- Expression of Vibrio vulnificus Capsular Polysaccharide Inhibits Biofilm FormationJournal of Bacteriology, 2004
- Identification of Genetic Loci Required for Capsular Expression in Vibrio vulnificusInfection and Immunity, 2003
- Molecular Cloning and Characterization of Genes for Shigella sonnei Form I O Polysaccharide: Proposed Biosynthetic Pathway and Stable Expression in a Live Salmonella Vaccine VectorInfection and Immunity, 2002
- Identification of thecadBAoperon fromVibrio vulnificusand its influence on survival to acid stressFEMS Microbiology Letters, 2002
- WbpO, a UDP-N-acetyl-d-galactosamine Dehydrogenase from Pseudomonas aeruginosa Serotype O6Published by Elsevier ,2000
- Construction and Phenotypic Evaluation of aVibrio vulnificus vvpEMutant for Elastolytic ProteaseInfection and Immunity, 2000
- Structure determination of the capsular polysaccharide from Vibrio vulnificus strain 6353European Journal of Biochemistry, 1998
- Nucleotide sequence of the kanamycin resistance transposon Tn903Journal of Molecular Biology, 1981
- A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye BindingAnalytical Biochemistry, 1976
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976