Juvenile Xanthogranuloma Associated with Neurofibromatosis 1: 14 Patients without Evidence of Hematologic Malignancies
- 1 March 2004
- journal article
- Published by Wiley in Pediatric Dermatology
- Vol. 21 (2) , 97-101
- https://doi.org/10.1111/j.0736-8046.2004.21201.x
Abstract
The clinical features and natural history of juvenile xanthogranuloma (JXG) in 14 children affected by neurofibromatosis 1 (NF1) are reported. Mean follow‐up in 11 of these patients was 4.3 years (range 1–10 years). None of the children developed hematologic malignancies during this period. The onset of JXG was in the first 2 years of life in 13 of the patients. In this series, the association between JXG and six or more café au lait spots more than 5 mm in diameter was a good marker for NF1 in the first few years of life. Overall the JXG in these patients did not show any features distinguishable from those of “classical” JXG.Keywords
This publication has 20 references indexed in Scilit:
- Juvenile xanthogranulomaJournal of the American Academy of Dermatology, 1997
- Juvenile xanthogranuloma, neurofibromatosis 1, and juvenile chronic myeloid leukemiaArchives of Dermatology, 1996
- Non-Langerhans Cell HistiocytosesThe American Journal of Dermatopathology, 1996
- Cutaneous Presentation of Juvenile Chronic Myelogenous Leukemia: A Diagnostic and Therapeutic DilemmaPediatric Dermatology, 1995
- Juvenile xanthogranuloma and acute leukemia: A case reportMedical and Pediatric Oncology, 1994
- Juvenile Xanthogranuloma and NeurofibromatosisPediatric Dermatology, 1991
- Juvenile chronic granulocytic leukemia, juvenile xanthogranulomas, and neurofibromatosis: Case report and review of the literatureJournal of the American Academy of Dermatology, 1990
- Histiocytic syndromes: A reviewJournal of the American Academy of Dermatology, 1985
- Association of juvenile xanthogranuloma with juvenile myeloid leukemiaArchives of Dermatology, 1984
- Neurofibromatosis and childhood leukemiaThe Journal of Pediatrics, 1978