METACHRONOUS BILATERAL WILMS TUMOR - NATIONAL WILMS TUMOR STUDY

  • 1 January 1982
    • journal article
    • research article
    • Vol. 5  (5) , 545-550
Abstract
Of the patients randomized for treatment according to the first and second National Wilms'' Tumor Studies, 18 have developed clinically evident tumor in the contralateral kidney subsequent to the initial diagnosis. Only 7 of 18 had an adequate exploration of the opposite kidney during the initial surgery and of these seven, 4 had abnormal findings. Thirteen of 18 cases showed some form of nephroblastomatosis histologically. The original tumors in 6, possibly 7, were multicentric in origin. While metachronous Wilms'' tumors are an unusual occurrence, the prognosis is ominous with only 7 of 18 surviving free of disease. The outlook might be improved with adequate attention to the surgical and histologic details during the initial diagnostic procedures.

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