Regression of AIDS-Related Kaposi's Sarcoma During Therapy with Thalidomide
Open Access
- 1 September 1996
- journal article
- case report
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 23 (3) , 501-503
- https://doi.org/10.1093/clinids/23.3.501
Abstract
A 14-year-old girl with HIV infection and subcutaneous Kaposi's sarcoma (KS) received thalidomide therapy for oral ulcers, resulting in regression of KS lesions, disappearance of KS-associated herpesvirus (KSHV) DNA from blood, and reduced viral load in tumor tissue. Administration of granulocyte colony-stimulating factor resulted in clinical exacerbation of KS and reappearance of KSHV DNA in blood.Keywords
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