RENAL CLEARANCE OF ESSENTIAL AMINO ACIDS: THEIR COMPETITION FOR REABSORPTION BY THE RENAL TUBULES

Abstract
Competition for reabsorption by the renal tubules was demonstrated to exist following the intraven. admn. of the amino acid pairs arginine and lysine, arginine and his-tidine, leucine and isoleucine. No competition for reabsorption was observed with the amino acid pairs arginine and gly-cine, leucine and glycine, isoleucine and glycine, and arginine and leucine. The results are interpreted to indicate the existence of at least 2 tubular mechanisms for the reabsorption of amino acids.

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