Iron Deficiency Anaemia and the Acid-Base Variations of Exercise

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Abstract
Two patients suffering from iron deficiency anaemia were given a standard exercise test of 500 kpm/min during 4 consecutive minutes before treatment was begun and after the anaemia had been corrected. The corresponding acid-base variations were more marked before iron therapy was started than afterwards. The conspicuous shifts in acid-base balance observed in anaemic patients performing muscular work reflect a certain degree of anaerobiosis. This anaerobic component of the energy metabolism disappears or becomes smaller when the blood transport capacity for oxygen is improved.

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