PGM1 subtypes determined by agarose gel isoelectrofocusing
- 1 September 1980
- journal article
- research article
- Published by Springer Nature in International journal of legal medicine
- Vol. 84 (3) , 221-224
- https://doi.org/10.1007/bf01866573
Abstract
PGM1 subtypes were determined in red cell hemolysates by isoelectric focusing on agarose gel plates. By this modified procedure PGM1 subtypes may be readily classified. Nine of the 10 expected phenotypes were found in a sample of 470 unrelated individuals from Southern Germany. The frequencies for the four alleles were found to be: PGM 1 1+ = 0.6212, PGM 1 1- = 0.1224, PGM 1 2+ = 0.2043, PGM 1 2- = 0.0521. Der PGM1-Polymorphismus wurde mit Hilfe der Isoelektrofokussierung auf Agarose-Gel-Platten untersucht. Mit dieser modifizierten Methode lassen sich die PGMI-Untergruppen an Hämolysaten ohne Schwierigkeiten klassifizieren. Neun der erwarteten zehn Phänotypen wurden in einer Stichprobe von. 470 nichtverwandten Personen aus Süddeutschland beobachtet. Folgende Allelhäufigkeiten wurden ermittelt: PGM 1 1+ = 0,6212, PGM 1 1- = 0,1224, PGM 1 2+ = 0,2043, PGM 1 2- = 0,0521.This publication has 9 references indexed in Scilit:
- Genetic Evidence for Four Common Alleles at the Phospho‐glucomutase‐1 Locus (PGM1) Detectable by Isoelectric FocusingVox Sanguinis, 1978
- Investigations on the PGM 1 a polymorphism (phosphoglucomutase-EC 2.7.5.1) by isoelectric focusingHuman Genetics, 1978
- PGM1 subtyping by means of acid starch gel electrophoresisHuman Genetics, 1978
- Isoelectric focusing of human red cell phosphoglucomutaseHuman Genetics, 1978
- Evidence for two additional common alleles at the PGM1 locus (Phosphoglucomutase-E.C.:2.7.5.1)Human Genetics, 1977
- Typing of the Common Phosphoglucomutase Variants Using Isoelectric Focusing—A New Interpretation of the Phosphoglucomutase SystemJournal of the Forensic Science Society, 1976
- Regional Localization of Loci for Human PGM 1 and 6PGD on Human Chromosome One by Use of Hybrids of Chinese Hamster-Human Somatic CellsProceedings of the National Academy of Sciences, 1973
- Linkage studies of enzyme markers in man-mouse somatic cell hybridsAnnals of Human Genetics, 1973
- Phosphoglucomutase Polymorphism in ManNature, 1964