Activation of NO donors in mitochondria: Peroxidase metabolism of (2‐hydroxyamino‐vinyl)‐triphenyl‐phosphonium by cytochrome c releases NO and protects cells against apoptosis
Open Access
- 5 February 2008
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 582 (5) , 725-728
- https://doi.org/10.1016/j.febslet.2008.01.047
Abstract
In mitochondrial apoptosis, the formation of cytochrome c–cardiolipin complex ([CL‐cyt c]) with peroxidase properties is an early event in the cascade of reactions that leads to cell death. Herein, w...Keywords
This publication has 11 references indexed in Scilit:
- Fluorescence Determination of Nitric Oxide Production in Stimulated and Activated PlateletsAnalytical Chemistry, 2007
- Nitric Oxide Inhibits Peroxidase Activity of Cytochrome c· Cardiolipin Complex and Blocks Cardiolipin OxidationJournal of Biological Chemistry, 2006
- Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factorsNature Chemical Biology, 2005
- Fine‐tuning the hydrophobicity of a mitochondria‐targeted antioxidantFEBS Letters, 2004
- Oxidation of the Ketoxime Acetoxime to Nitric Oxide by Oxygen Radical-Generating SystemsNitric Oxide, 2001
- Drug delivery to mitochondria: the key to mitochondrial medicineAdvanced Drug Delivery Reviews, 2000
- Microsomal Cytochrome P450 Dependent Oxidation of N-Hydroxyguanidines, Amidoximes, and Ketoximes: Mechanism of the Oxidative Cleavage of Their CN(OH) Bond with Formation of Nitrogen OxidesBiochemistry, 1998
- Detection and Imaging of Nitric Oxide with Novel Fluorescent Indicators: DiaminofluoresceinsAnalytical Chemistry, 1998
- Mechanism of Radical Production from the Reaction of Cytochrome c with Organic Hydroperoxides.Journal of Biological Chemistry, 1995
- Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobinLipids, 1992