The kapurimycins, new antitumor antibiotics produced by Streptomyces. Physico-chemical properties and structure determination.
- 1 January 1990
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 43 (12) , 1519-1523
- https://doi.org/10.7164/antibiotics.43.1519
Abstract
The kapurimycins A1, A2 and A3 were revealed to be new antitumor antibiotics with molecular formula of C27H26O9, C26H24O9 and C27H24O9, respectively. The structures of the kapurimycins were determined by NMR spectroscopic analysis. The kapurimycins are new class of polycyclic microbial metabolites having the tetrahydroanthra-gamma-pyrone skeleton and the beta,gamma-unsaturated delta-keto carboxylic acid structure. The individual components of the kapurimycins differ from one another in the side chain at the pyrone ring of the molecule.This publication has 3 references indexed in Scilit:
- The kapurimycins, new antitumor antibiotics produced by Strepromyces. Producing organism, fermentation, isolation and biological activities.The Journal of Antibiotics, 1990
- The structure of the antibiotic hedamycin-IITetrahedron, 1978
- STUDIES ON ANTITUMOR SUBSTANCES PRODUCED BY ACTINOMYCETES .11. A NEW ANTITUMOR SUBSTANCE, PLURAMYCIN1956