Alcohol Self-Administration Disrupts Reproductive Function in Female Macaque Monkeys
- 12 August 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 221 (4611) , 677-679
- https://doi.org/10.1126/science.6867739
Abstract
Female macaque monkeys self-administered high doses of alcohol (2.9 to 4.4 grams per kilogram per day) for 3 to 6 1/2 months. Amenorrhea, atrophy of the uterus, decreased ovarian mass, and significant depression of luteinizing hormone levels were associated with chronic alcohol intoxication. Reproductive system failure in female primates following self-induced dependence on alcohol parallels the results of clinical studies of alcoholic women.This publication has 12 references indexed in Scilit:
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