Carbohydrate Homeostasis

Abstract
Role of Extrahepatic TissuesThe KidneyIt has been known for many years that the kidney is an auxiliary glucose-producing organ. This fact was first appreciated when the fall in blood sugar after hepatectomy was compared with the reduction that followed combined hepatectomy and nephrectomy. Other ways of detecting the glucose-producing power of the kidney are the measurement of blood flow and arteriovenous differences across the kidney, in vitro incubation of kidney slices with lactate and amino acids and kidney perfusions.17, 70 Under normal conditions, the kidneys are a site of glucose utilization rather than glucose production, according to catheterization studies . . .