Isolation and Characterization of MC3T3-E1 Preosteoblast Subclones with Distinct In Vitro and In Vivo Differentiation/Mineralization Potential
Open Access
- 1 June 1999
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Bone and Mineral Research
- Vol. 14 (6) , 893-903
- https://doi.org/10.1359/jbmr.1999.14.6.893
Abstract
A series of subclonal cell lines with high or low differentiation/mineralization potential after growth in the presence of ascorbic acid (AA) were derived from murine MC3T3-E1 cells. Subclones were c...Keywords
This publication has 54 references indexed in Scilit:
- The Mature Osteoblast Phenotype Is Characterized by Extensive PlasticityExperimental Cell Research, 1997
- Bone sialoprotein knockout mice have bone abnormalitiesBone, 1995
- Fibronectin gene expression, synthesis, and accumulation during in vitro differentiation of chicken osteoblastsJournal of Bone and Mineral Research, 1995
- Mineralization of bone-like extracellular matrix in the absence of functional osteoblastsJournal of Bone and Mineral Research, 1995
- Alteration of Bone Status with Ascorbic Acid Deficiency in ODS (Osteogenic Disorder Shionogi) RatsThe Japanese Journal of Pharmacology, 1995
- Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cellsJournal of Bone and Mineral Research, 1994
- Bone morphogenetic protein-2b stimulation of growth and osteogenic phenotypes in rat osteoblast-like cells: Comparison with TGF-β1Journal of Bone and Mineral Research, 1991
- Expression of differentiated function by mineralizing cultures of chicken osteoblastsDevelopmental Biology, 1987
- Subclone heterogeneity in a clonally-derived osteoblast-like cell lineBone, 1985
- In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria.The Journal of cell biology, 1983