Polymorphism of genomic RNAs within rotavirus serotypes and subgroups
- 1 March 1982
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 74 (1) , 65-70
- https://doi.org/10.1007/bf01320783
Abstract
The genome of human rotaviruses is composed of 11 segments of double stranded RNA. Analysis by polyacrylamide gel electrophoresis of the genomic RNA from a number of strains of the same serotype has demonstrated a significant polymorphism in the migration pattern. However, two strains differing from each other in serotype were found to have apparently identical RNA migration patterns. It is concluded that serotype cannot be deduced from RNA migration patterns. Degrees of polymorphism have been observed within each of three known human rotavirus serotypes.Keywords
This publication has 7 references indexed in Scilit:
- Serotyping and subgrouping of rotavirus strains by the ELISA testArchiv für die gesamte Virusforschung, 1982
- Antigenic relationships between rotaviruses from different species as studied by neutralization and immunofluorescenceArchiv für die gesamte Virusforschung, 1982
- Rotavirus serotypes by serum neutralisationJournal of Medical Virology, 1980
- Serological relationships between rotaviruses from different species as studied by complement fixation and neutralizationArchiv für die gesamte Virusforschung, 1977
- A Microtiter Solid Phase Radioimmunoassay for Detection of the Human Reovirus-Like Agent in StoolsThe Journal of Immunology, 1977
- Antigenic Relationships among Five Reovirus-Like (RVL) Agents by Complement Fixation (CF) and Development of New Substitute CF Antigens for the Human RVL Agent of Infantile GastroenteritisExperimental Biology and Medicine, 1976