The Treatment of Occlusive Arterial Disease
- 19 January 1963
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 183 (3) , 186-191
- https://doi.org/10.1001/jama.1963.63700030004014
Abstract
THROUGHOUT his entire existence, man is poised delicately and dangerously as on the two-faced escarpment of a mountain; on one side there is the risk of hemorrhage and on the other side the deadly threat of thrombosis. By a remarkable and complex combination of chemical and physical processes, both hemorrhage and thrombosis occur almost incessantly and simultaneously in different parts of his vascular tree; yet only rarely in his lifetime does he slip off his precarious perch to a catastrophic injury or death. And, of the two, the risk of death or disability due to thrombosis or embolism is far greater than that due to hemorrhage. This article will discuss these aspects of occlusive arterial disease. The most common causes of arterial occlusion are thrombosis at the site of an atherosclerotic plaque and embolism due to a fibrillating or infarcted heart. These episodes may be acute, the critical phaseKeywords
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