Environmentally friendly synthesis of coumarin derivatives employing heterogeneous catalysis

Abstract
Zeolite H‐BEA and other solid acids have been shown to be effective catalysts for the production of coumarin derivatives from activated phenols and acids or esters possessing an additional alkylation function, or β‐keto esters (Pechmann reaction). These heterogeneous catalysts eliminate the production of acidic waste streams associated with conventional (Lewis) acid catalysts. Zeolite H‐BEA proved to be the preferred catalyst.
Funding Information
  • Dutch Innovation Orientated Research Program on Catalysis